Phenyl HP Columns

Description

Phenyl HP Columns from G Biosciences are chromatography columns designed for hydrophobic interaction chromatography (HIC). These columns are used in the purification and separation of biomolecules, particularly proteins, based on differences in surface hydrophobicity. The phenyl-functionalized stationary phase interacts with hydrophobic regions on protein surfaces under high-salt conditions, enabling the optimization of purification strategies. This technique is often employed as a polishing step in downstream bioprocessing to remove aggregates, misfolded variants, or other impurities. The columns are suitable for method development and scale-up processes in both research and industrial applications involving therapeutic proteins, antibodies, and enzymes.