Nexera Preparative Supercritical Fluid Chromatography System

Description

The Nexera Preparative Supercritical Fluid Chromatography (Prep SFC) System is designed for semi-preparative purification using supercritical CO2 as the primary mobile phase. It is noted for its compact design, which conserves laboratory bench space. The system offers configurable components, with flow rates and maximum pressure limits dependent on the specific pump modules selected. Detection is typically performed using UV/VIS or photodiode array (PDA) detectors. A highlighted technology is the patented LotusStream gas-liquid separator (GLS), which is implemented to achieve high recovery rates of purified fractions while minimizing sample carryover and simplifying the rinsing process compared to older cyclone or centrifugal designs. The system includes a stacked injection function, allowing for sequential sample injections without intervening delay to increase throughput. The integrated software provides dedicated preparative settings to guide method setup and fraction collection, intended for reliable operation by users across a spectrum of expertise. A wide selection of columns is available for both analytical and preparative scale separations.