Multisizer 4e Coulter Counter

Description

The Multisizer 4e from Beckman Coulter Life Sciences is a particle sizer and counter based on the Coulter principle of electrical zone sensing. This method allows for the detection and sizing of particles based on their volume, independent of their shape, composition, or optical properties. The instrument is designed to handle a wide range of sample types, including biological and non-biological materials in both aqueous and non-aqueous solvents. Its operational sizing range spans from 0.2 to 1600 micrometers in diameter, facilitated by a selection of aperture tubes ranging from 10 to 2000 micrometers. A notable feature is the availability of a 10-micrometer aperture, which enables the analysis of sub-micron particles down to approximately 200 nm. The system utilizes digital pulse processing technology to capture high-resolution data, which can be stored and re-analyzed as needed. Sample volumes are continuously selectable from 50 µL to 2000 µL, and the device can achieve counting rates up to 10,000 particles per second. It is suitable for applications involving mammalian cells, bacteria, yeast, abrasives, toner, cell aggregates, and protein aggregates. The accompanying software is compliant with CFR 21 Part 11 regulations for data integrity and security.