MetaXpress High Content Image Acquisition & Analysis Software

Description

MetaXpress is a high-content image acquisition and analysis software platform from Molecular Devices, LLC. It provides an integrated workflow for capturing, processing, and quantifying cellular and subcellular images from automated microscopes, supporting both 2D and 3D experimental models. The software includes a suite of application modules tailored for specific assay types, ranging from predefined protocols for ease of use to a Custom Module Editor that allows researchers to design proprietary analysis routines. For 3D imaging, the platform offers tools for acquiring Z-stacks and performing volumetric analysis, enabling measurements of parameters like spheroid volume, fluorescence intensity, and object distances within three-dimensional samples. Acquisition capabilities support time-lapse experiments, with a patented fast frame rate mode capable of capturing up to 50 frames per second to monitor rapid biological processes. Analysis features include intelligent segmentation algorithms for both fluorescently labeled and label-free images. To handle large datasets, an optional parallel processing module (MetaXpress PowerCore) can significantly accelerate analysis runtime. Included data management is handled by MDCStore Data Manager, which organizes images, experimental metadata, and results. For advanced informatics, the optional AcuityXpress platform provides tools for in-depth data mining, statistical analysis, and visualization, seamlessly integrating with the core MetaXpress database.