JEM-Z200FSC CRYO ARM200 Field Emission Cryo-electron Microscope

Description

The JEM-Z200FSC CRYO ARM200 is a dedicated cryo-electron microscope for structural biology, specifically optimized for single-particle analysis workflows. It operates at a 200 kV accelerating voltage and is engineered for high stability to facilitate the collection of high-resolution data from vitrified biological specimens. The system is capable of achieving atomic resolution, with examples cited at 1.53 Å. It is typically configured with a Gatan K2 direct electron detector, which at a magnification of 100,000x provides an image pixel size of 0.495 Å. Key automation features include auto-focus, coma-free alignment, and automated parallel-beam illumination adjustment. The instrument incorporates a cold field emission gun, an in-column energy filter (Omega-type), and an automated specimen exchange system to maintain sample integrity at cryogenic temperatures. These features, combined with dedicated software for automated image acquisition, are intended to enable efficient and unattended data collection for determining the three-dimensional structures of proteins, viruses, and other macromolecular complexes.