ISOLUTE® PLD+ Protein and Phospholipid Removal Plates

Description

ISOLUTE PLD+ Protein and Phospholipid Removal Plates provide a simplified sample preparation method for LC-MS/MS analysis. Utilizing a solvent crash and filtration procedure, these plates simultaneously remove proteins and phospholipids from plasma and other blood-based samples. This clean-up is achieved in three basic steps without the need for complex conditioning or washing protocols. The process maintains high and reproducible analyte recoveries while effectively eliminating matrix components that can interfere with instrument sensitivity and performance. The plates exhibit excellent flow characteristics, making them compatible with various processing systems, including positive pressure, vacuum manifolds, and automated liquid handlers. They are applicable in pharmaceutical bioanalysis, forensic testing, and clinical diagnostics.