ddSEQ™ Single-Cell Isolator

Description

Bio-Rad's ddSEQ Single-Cell Isolator is a microfluidic instrument designed to encapsulate individual cells within nanoliter-sized droplets. This method of isolation is a key preparatory step for generating single-cell libraries intended for genomic analysis, particularly RNA sequencing. Unlike traditional cell sorters, this system does not use fluorescence-activated sorting but instead relies on droplet partitioning. A primary operational characteristic is its throughput, which enables the processing of several hundred to tens of thousands of cells in a single day. This capacity makes the instrument applicable for single-cell transcriptomics studies, where capturing cellular heterogeneity with minimal bias is important. The workflow integrates with specific consumables and reagents to prepare samples for sequencing platforms.