ClonePix 2 Mammalian Colony Picker

Description

The ClonePix 2 Mammalian Colony Picker is an automated instrument from Molecular Devices used to isolate and transfer mammalian cell colonies. It is primarily applied in cell line development for applications like monoclonal antibody generation. This system automates the identification and selection of clones by imaging culture plates and using robotic tools to pick colonies. A key feature is its ability to perform in situ secretion assays, allowing researchers to screen colonies based on the levels of protein or antibody they secrete. This method can serve as an alternative to traditional limiting dilution, potentially accelerating the process of finding high-producing cell lines and providing early expression data to filter out low performers.