BIOshell™ UHPLC and HPLC Columns for Biomolecules

Description

Merck KGaA's BIOshell columns are engineered for the chromatographic separation of biological molecules using both UHPLC and HPLC systems. These columns incorporate superficially porous silica particles, a design often referred to as Fused-Core technology. A key characteristic is the availability of multiple pore sizes, spanning from 90 Å to 1000 Å. This broad range allows the columns to accommodate a diverse array of biomolecules, from small glycans to large proteins and monoclonal antibodies with molecular weights exceeding 100 kDa. The particle architecture is intended to deliver efficient separations at high speeds, making these columns applicable for rigorous analytical workflows in life sciences research.