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DNA Sequencers / Genetic AnalyzersGenomics Tools

AXELIOS 1 Platform

Manufacturer: Roche

Model: SYS_597

Description

The AXELIOS 1 Platform is Roche's next-generation sequencing (NGS) system built on Sequencing by Expansion (SBX) technology for high-throughput single-molecule sequencing. SBX decouples synthesis from measurement, enabling real-time single-molecule sequencing on a specialized CMOS sensor array rather than traditional iterative cycles. The platform comprises three main components: the Synthesis Instrument (converts DNA libraries into Xpandomer molecules), the Sequencing Instrument (performs electrical measurement through nanopore-based sensors), and the Platform Manager (locally hosted software for configuration and management). For Research Use Only.

Specifications

TechnologySequencing by Expansion (SBX), single-molecule
ComponentsSynthesis Instrument, Sequencing Instrument, Platform Manager
SensorCMOS sensor array, over 8 million wells
Output (SBX-D)≥ 1.8 Tb per 4-hour run
Accuracy~Q38 (concordant duplex bases)
Read length~200–1500 bp
Throughput~16 human genomes per 4-hour run at 30x coverage
Run time15 minutes to 4 hours (up to 22 hours for 4 queued runs)
Synthesis Instrument780 mm W × 810 mm H × 675 mm D; 108 kg; 100-120V/220-240V, 50/60 Hz
Sequencing Instrument1380 mm W × 1644 mm H × 760 mm D; 438 kg; 2 × 200-240V AC, 50/60 Hz, 30A
Network2 × 10 Gbps (dedicated connection recommended)
UseResearch Use Only

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