Acetonitrile with 0.1% Trifluoroacetic Acid (v/v), HPLC Grade, Fisher Chemical

Description

A high-performance liquid chromatography (HPLC) grade solvent, this blend is acetonitrile mixed with 0.1% trifluoroacetic acid (TFA) by volume. It is provided in a 4-liter amber glass bottle featuring EcoSafPak packaging for enhanced safety. The primary CAS number associated with the acetonitrile component is 75-05-8. Trifluoroacetic acid is a strong ion-pairing reagent frequently used in the separation of peptides, proteins, and other biomolecules via reversed-phase HPLC. This pre-formulated mixture offers a consistent concentration of TFA, which is critical for maintaining reproducible chromatographic conditions, including baseline stability and peak symmetry, particularly when analyzing acidic compounds or performing peptide mapping.